Postdoctoral position: Functionnalization and self-assembly of filamentous bacteriophages [avant 01 octobre 2014)
01/07/2014 17:05
A postdoctoral position is available in Bordeaux (France) to develop the functionnalization of the M13 bacteriophages and to study the self-assembly and phase behavior of such chemically modified phages. The candidate must be motivated by interdisciplinary projects and should have an expertise in surface functionnalization and/or bioconjugate chemistry, as well as interest for self-assembly. Topic: The use of bionanoparticles and more specifically of viruses or phages, as building blocks for generating highly organized materials with hierarchical structures, is an emerging field in material science and biotechnology, because of unique features and advantages exhibited by viral particles: high degree of symmetry, uniformity in size and shape, well-characterized surface chemistry, ease of production, robustness, biocompatibility... Viruses and phages appear therefore as versatile and functional organic protein-based supramolecules for chemists and as model structural entities for soft matter physicists. In this context, we aim to use the specificity of reactive chemical functions on viral surface to regio-functionalize the M13 phages in order to develop a new generation of chemically modified virus based particles exhibiting a dynamic control of their properties. Our goal is to introduce stimulus –responsive features onto viral platforms, to create for instance temperature responsive patchy particles, paving therefore the way for the elaboration of original self-assemblies. The position (between 1 and 3 years) is founded by the French National Research Agency (ANR). Salary is competitive, depending on the candidate qualification.
- Organisé par: Centre de Recherche Paul-Pascal, CNRS Université de Bordeaux
- Contact(s): grelet@crpp-bordeaux.cnrs.fr
- Lien Web: https://www.crpp-bordeaux.cnrs.fr