Protein Epistasis Revealed from Thermostability Profiles of Nicotiana tabacum 5-epi-Aristolochene Synthase
01/04/2013 00:00
Charisse Crenshaw, Johnatan Aljadeff, Irma Fernandez, Caroline Laurendon, Marianne Defernez, Hyun Jo Koo, Paul E. O’Maille, Tatyana Sharpee and Joseph P. Noel
Résumé:
The limits of protein evolution are ultimately defined by biophysical constraints. Specifically, the maintenance of protein...